Uma Arora
I’m a computational biologist with a PhD in genetics and a passion for making sense of complex biological data. My work bridges evolutionary genomics and cancer biology—whether it’s decoding repetitive DNA in obscure mouse centromeres or uncovering hidden signals in large-scale human cohort data. Over the past few years, I’ve applied machine learning, multi-omics integration, and statistical genetics to tackle questions in hematopoiesis, early cancer detection, and translational research. I enjoy building scalable pipelines, wrangling high-dimensional datasets, and turning raw sequencing files into biological insights. Proficient in Python, R, and cloud/HPC systems, I thrive in interdisciplinary teams and love collaborating with wet-lab scientists, clinicians, and fellow data nerds alike.
Portfolio
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Quantifying rare variant risk
Utilizing the UK Biobank to estimate risk of rare ClinVar variants for MPN
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META GWAS
Identify novel variants responsible for fetal hemoglobin regulation and MPN
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Rare Variant Association
Discovering novel mechanisms underlying risk for myeloid malignancies
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CENP-A ChIP-seq
CENP-A sequence association landscape differences between mouse strains
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K-mer estimation of mouse centromere size
My first independent project in graduate school
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Skin microbiome and acne
How porphyrin production can influence inflammation by the skin microbiome
Blog
- 2025-06-03» Polygenic Modifiers Impact Penetrance And Expressivity In Telomere Biology Disorders
- 2024-02-01» Inherited Blood Cancer Predisposition Through Altered Transcriptional Elongation
- 2023-11-15» Centromere Innovations Within A Mouse Species
- 2023-10-31» Variation In The Cenpa Sequence Association Landscape Across Diverse Inbred Mouse Strains
- 2021-11-19» Selection Shapes The Landscape Of Functional Variation In Wild Mice
- 2021-04-17» Population And Subspecies Diversity At Mouse Centromeres
- 2020-01-15» Porphyrin Production And Regulation In Cutaneous Propionibacteria
Volunteer
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Conservation Education
NEW
Educate New England Aquarium visitors about the importance of protecting the blue planet
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Carpentries Instructor
Teaching foundational data science and coding skills to researchers worldwide
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Phytoplankton Monitoring
Monitoring harmful algal blooms in the gulf of Maine